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STS2 / TULA (aa470-482) Antibody (internal region)品牌 |
Leading Biology | 貨號(hào) |
APG00759G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality STS2 / TULA (aa470-482) Antibody (internal region).
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分子量 |
74123 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus.
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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亞型 |
IgG
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通用名 |
STS2
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基因ID |
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UniProt ID |
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功能 |
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
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總結(jié) |
This antibody is expected to recognize both reported isoforms (NP_061834.1; NP_001001895.1).
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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圖像 |
APG00759G (1 μg/ml) staining of Human Spleen lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. APG00759G (3.8 μg/ml) staining of paraffin embedded Human Breast. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |
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說(shuō)明書(shū) |
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數(shù)量 |
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