全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APG00394G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BS69 / ZMYND11 Antibody (N-Term).
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分子量 |
70963 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Chromosome. Note=Associates with chromatin and mitotic chromosomes
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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亞型 |
IgG
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通用名 |
BRAM1, BS69
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基因ID |
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UniProt ID |
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功能 |
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
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總結(jié) |
This antibody is expected to recognise all reported human isoforms (NP_006615.2; NP_997644.2; NP_001189393.1; NP_001189394.1; NP_001189395.1; NP_001189396.1; NP_001189397.1).
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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說(shuō)明書 |
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數(shù)量 |
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