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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-NFIL3 Antibody

Goat Anti-NFIL3 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APG00219G 0.1mg / ¥4950

Goat Anti-NFIL3 Antibody

品牌

Leading Biology

貨號(hào)

APG00219G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-NFIL3 Antibody.

分子量

51472 Da

細(xì)胞定位

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}

宿主

Goat

種屬反應(yīng)性

Human

亞型

IgG

通用名

E4BP4, IL3BP1

基因ID

UniProt ID

功能

Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B- site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death (By similarity).

總結(jié)

Expression of interleukin-3 (IL3; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995 [PubMed 7565758]).

形式

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

圖像

APG00219G staining (0.5 μg/ml) of HepG2 lysate (RIPA buffer, 20 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

說(shuō)明書(shū)

數(shù)量

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