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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-MIF Antibody

Goat Anti-MIF Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APG00201G 0.1mg / ¥4950

Goat Anti-MIF Antibody

品牌

Leading Biology

貨號

APG00201G

產(chǎn)品分類

Polyclonal Antibodies

研究領域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-MIF Antibody.

分子量

12476 Da

細胞定位

Antigen Cellular Localization: Secreted. Cytoplasm. Note=Does not have a cleavable signal sequence and is secreted via a specialized, non- classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens

宿主

Goat

種屬反應性

Human

亞型

IgG

通用名

GLIF, MMIF

基因ID

UniProt ID

功能

Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti- inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

總結

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.

形式

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, E, EIA

圖像

APG00201G (0.01 μg/ml) staining of Human Thymus lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

APG00201G (0.01 μg/ml) staining of Daudi (A) and Jurkat (B) lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

APG00201G (1.5ug/ml) as the reporter with EB002005 as the capture rabbit antibody (5ug/ml).

說明書

數(shù)量

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