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全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR00231G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GLUT4 Antibody.
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分子量 |
54755 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration (By similarity).
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse, Rat
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靶點(diǎn) |
GLUT4
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亞型 |
Rabbit IgG
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通用名 |
Glut-4, Glut4
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基因ID |
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UniProt ID |
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功能 |
Insulin-regulated facilitative glucose transporter.
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總結(jié) |
Insulin stimulates glucose uptake in the muscles and adipose tissues by activating GLUT4 (Glucose Transporter Type 4). GLUT 4 is a transmembrane protein that facilitates glucose transport from storage sites to cell surface. Human insulin resistance involves a defect in GLUT4 that leads to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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說(shuō)明書(shū) |
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數(shù)量 |
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