品牌 |
Leading Biology |
貨號 |
APR00226G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Adipsin Antibody.
|
分子量 |
28057 Da
|
細胞定位 |
Antigen Cellular Localization:
Secreted.
|
宿主 |
Rabbit
|
種屬反應性 |
Mouse, Rat
|
靶點 |
Adipsin
|
亞型 |
Rabbit IgG
|
通用名 |
Adn, Df
|
基因ID |
|
UniProt ID |
|
功能 |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
|
總結(jié) |
Adipsin is a serine protease secreted by adipose tissue, and it has also been found in monocytes/macrophages. Adipsin has been identified to be similar to complement Factor D. Adipsin cleaved complement Factor B when the later form complexed with activated complement component C3. Low level expression of Adipsin has been linked to obesity in mouse model s μggesting that defects in Adipsin is the result of this systemic disorder.
|
形式 |
Liquid
|
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應用 |
WB
|
圖像 |
Western blot analysis of Adipsin with rat kidney tissue lysate.
|
說明書 |
|
數(shù)量 |
|