全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR00224G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TLR10 Antibody.
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分子量 |
94564 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat, Bovine
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靶點 |
TLR10
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亞型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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功能 |
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
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總結(jié) |
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is homologous to TLRs 1 and 6 and is highly expressed in the lymphoid tissues.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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圖像 |
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說明書 |
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數(shù)量 |
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