全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR00218G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Dectin-1 Antibody.
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分子量 |
27627 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Single- pass type II membrane protein Isoform 6: Cytoplasm.
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
Dectin-1
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亞型 |
Rabbit IgG
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通用名 |
BGR, CLECSF12, DECTIN1
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基因ID |
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UniProt ID |
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功能 |
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
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總結(jié) |
Dectin-1also known as beta-glucan receptor is a small type II transmembrane receptor containing lectin-like carbohydrate recognition domain. Dectin-1 plays a role in beta-glucan dependant, nonopsonic recognition of zymosan by primary macropahge. Dectin-1 is expressed on macrophages and neutrophils and on some dendritic cells subpopulation.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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說明書 |
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數(shù)量 |
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