全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR00134G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Wnt-6 Antibody.
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分子量 |
39656 Da
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細胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
Wnt-6
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亞型 |
Rabbit IgG
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通用名 |
Wnt-6
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基因ID |
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UniProt ID |
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功能 |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
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總結 |
Wnt gene family members, including Wnt-1 thro μgh Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-6 is involved in oncogenesis and is co-expressed with Wnt10 in colorectal cancer cell lines. The presence of cervical and breast cell carcinomas may indicate an over expression of Wnt-6.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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說明書 |
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數(shù)量 |
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