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RasGAP Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APR00065G 100 μg / ¥4950

RasGAP Antibody

品牌

Leading Biology

貨號

APR00065G

產品分類

Polyclonal Antibodies

研究領域

產品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RasGAP Antibody.

分子量

116403 Da

細胞定位

Antigen Cellular Localization: Cytoplasm.

宿主

Rabbit

種屬反應性

Human, Mouse, Rat, Bovine

靶點

RasGAP

亞型

Rabbit IgG

通用名

GAP, RASA

基因ID

UniProt ID

功能

Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1.

總結

The mammalian proto-oncogene Ras encodes 21 kDa proteins (p21Ras) which exists in either a physiologically quiescent GDP-binding state or a GTPbinding signal-emitting state. Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold. The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, IHC, IP

說明書

數(shù)量

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