p63 Antibody

APR00531G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR00531G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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p63 Antibody

品牌	Leading Biology	貨號(hào)	APR00531G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality p63 Antibody .
分子量	40kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Endosome membrane. Note=Interaction with PIP5K3 and subsequent phosphorylation recruits it to the endosomal membrane
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	A synthetic peptide (ENNAQTQFSEPQY) corresponding to aa5-17 of human p40
克隆號(hào)	N/A
亞型	IgG
通用名	RAB9P40
基因ID	10244
UniProt ID	Q7Z6M1
功能	Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
總結(jié)	p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody’s ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.
形式	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF, FC, IP
圖像	Formalin-paraffin lung squamous cell carcinoma stained with p40 Rabbit PAb Western blot analysis of p40 (p63 delta) in HEK293 lysate in 1) absence and 2) presence of immunizing peptide using p40 Rabbit PAb.
說(shuō)明書(shū)	Product Datasheet Protocol
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