HSP90AB1 Antibody (Center)

APR06022G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR06022G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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HSP90AB1 Antibody (Center)

品牌	Leading Biology	貨號	APR06022G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HSP90AB1 Antibody (Center).
分子量	83264 Da
細胞定位	Antigen Cellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
宿主	Rabbit
種屬反應性	Human
免疫原	438-465 aa
靶點	This HSP90AB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-465 amino acids from the Central region of human HSP90AB1.
亞型	Rabbit Ig
通用名	HSP90B, HSPC2, HSPCB
基因ID	3326
UniProt ID	P08238
功能	Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
總結(jié)	HSPCB are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. This protein normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
圖像	HSP90AB1 Antibody (Center) (Cat. APR06022G) western blot analysis in A431,Hela,L6 cell line lysates (35ug/lane).This demonstrates the HSP90AB1 antibody detected the HSP90AB1 protein (arrow). Formalin-fixed and paraffin-embedded human testis tissue reacted with HSP90AB1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Flow cytometric analysis of WiDr cells using HSP90AB1 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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