品牌 |
Leading Biology | 貨號(hào) |
APR05920G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CDC7 (CDC7L1) Antibody (N-term).
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分子量 |
63888 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
1-30 aa
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靶點(diǎn) |
This CDC7 (CDC7L1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC7 (CDC7L1).
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亞型 |
Rabbit Ig
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通用名 |
CDC7L1
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基因ID |
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UniProt ID |
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功能 |
Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
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總結(jié) |
CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
HCDC7L1 Antibody (M9) (Cat. APR05920G) western blot analysis in HT29,MCF-7 cell line lysates (35ug/lane).This demonstrates the HCDC7L1 antibody detected the HCDC7L1 protein (arrow). HCDC7L1 Antibody (M9) (Cat. APR05920G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HCDC7L1 antibody detected the HCDC7L1 protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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選擇 | 品牌 | 貨號(hào) | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說(shuō)明書(shū) | 數(shù)量 | 目錄價(jià) | |
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