GRB2 Antibody (Y209)

APR05738G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR05738G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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GRB2 Antibody (Y209)

品牌	Leading Biology	貨號(hào)	APR05738G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRB2 Antibody (Y209).
分子量	25206 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Endosome. Golgi apparatus
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	187-216 aa
靶點(diǎn)	This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
亞型	Rabbit Ig
通用名	ASH
基因ID	2885
UniProt ID	P62993
功能	Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
總結(jié)	GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
圖像	Western blot analysis of lysate from Ramos cell line, using GRB2 Antibody (pY209)(APR05738G). APR05738G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GRB2 Antibody (Y209), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
說(shuō)明書(shū)	Product Datasheet Protocol
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