品牌 |
Leading Biology | 貨號(hào) |
APR05658G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality STEA2 Antibody (Center).
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分子量 |
56056 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
226-253 aa
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靶點(diǎn) |
This STEAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the Central region of human STEAP2.
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亞型 |
Rabbit Ig
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通用名 |
PCANAP1, STAMP1
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基因ID |
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UniProt ID |
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功能 |
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
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總結(jié) |
This gene is a member of the STEAP family and encodes amulti-pass membrane protein that localizes to the Golgi complex,the plasma membrane, and the vesicular tubular structures in thecytosol. A highly similar protein in mouse has both ferrireductaseand cupric reductase activity, and stimulates the cellular uptakeof both iron and copper in vitro. Increased transcriptionalexpression of the human gene is associated with prostate cancerprogression. Alternate transcriptional splice variants, encodingdifferent isoforms, have been characterized.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:500
IHC-P~~1:50~100
FC~~1:10~50
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圖像 |
Western blot analysis of lysates from 293, HepG2 cell line, mouse spleen tissue lysate (from left to right), using STEAP2 Antibody (Center)(APR05658G). APR05658G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane. Western blot analysis of extracts from 293 (lanes 1 and 2),HepG2 (lanes 3 and 4)cell line and mouse spleen (lanes 5 and 6)tissue lysate: 1, 3, 5. using STEAP2 Antibody (Center)( APR05658G), (1:500). 2, 4, 6. using STEAP2 Antibody (Center), preincubated with the control peptide antigen. STEAP2 Antibody (Center) (Cat. APR05658G) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STEAP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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