UBE2L6 Antibody (N-term)

APR04797G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR04797G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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UBE2L6 Antibody (N-term)

品牌	Leading Biology	貨號	APR04797G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBE2L6 Antibody (N-term).
分子量	17769 Da
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	1-30 aa
靶點	This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBE2L6.
亞型	Rabbit Ig
通用名	UBCH8
基因ID	9246
UniProt ID	O14933
功能	Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
總結(jié)	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100
圖像	Western blot analysis of lysate from HL-60 cell line, using UBE2L6 Antibody (M1) (APR04797G). AP2118A was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with UBE2L6 Antibody (N-term)(Cat.APR04797G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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