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ZNF281 Antibody (Center)

APR04782G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR04782G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ZNF281 Antibody (Center)

品牌	Leading Biology	貨號	APR04782G
產品分類	Polyclonal Antibodies	研究領域
產品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZNF281 Antibody (Center).
分子量	96915 Da
細胞定位	Antigen Cellular Localization: Nucleus.
宿主	Rabbit
種屬反應性	Human, Mouse
靶點	This ZNF281 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 416-450 amino acids from the Central region of human ZNF281.
亞型	Rabbit Ig
通用名	GZP1, ZBP99
基因ID	23528
UniProt ID	Q9Y2X9
功能	Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G- rich box in the enhancer region of these genes.
總結	Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G- rich box in the enhancer region of these genes.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, E
稀釋方法	WB~~1:1000
圖像	Western blot analysis of lysates from Hela, A549, MCF-7 cell line, mouse liver, mouse small intestine tissue lysate(from left to right), using ZNF281 Antibody (Center)(APR04782G). APR04782G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
說明書	Product Datasheet Protocol
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