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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > CD44 Antibody (C-term)

CD44 Antibody (C-term)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR04683G 100 μl / ¥4950

CD44 Antibody (C-term)

品牌

Leading Biology

貨號(hào)

APR04683G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD44 Antibody (C-term).

分子量

81538 Da

細(xì)胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.

宿主

Rabbit

種屬反應(yīng)性

Human

靶點(diǎn)

This CD44 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 688-722 amino acids from the C-terminal region of human CD44.

亞型

Rabbit Ig

通用名

LHR, MDU2, MDU3, MIC4

基因ID

UniProt ID

功能

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

總結(jié)

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

圖像

Western blot analysis of lysates from Hela, PC-3, HT-1080 cell line (from left to right), using CD44 Antibody (C-term)(APR04683G). APR04683G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

說(shuō)明書

數(shù)量

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