SMAD1 Antibody (Center)

APR04642G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR04642G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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SMAD1 Antibody (Center)

品牌	Leading Biology	貨號	APR04642G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SMAD1 Antibody (Center).
分子量	52260 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點	This SMAD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 163-196 amino acids from the Central region of human SMAD1.
亞型	Rabbit Ig
通用名	BSP1, MADH1, MADR1
基因ID	4086
UniProt ID	Q15797
功能	Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
總結(jié)	Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
稀釋方法	IF~~1:25 IHC-P~~1:25 WB~~1:1000
圖像	Fluorescent image of MCF-7 cells stained with SMAD1 Antibody (Center)( APR04642G). APR04642G was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor? 555 conjugated with Phalloidin (red). Immunohistochemical analysis of paraffin-embedded H. heart section using SMAD1 Antibody (Center)( APR04642G). APR04642G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining. Immunohistochemical analysis of paraffin-embedded H. skeletal muscle section using SMAD1 Antibody (Center)( APR04642G). APR04642G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
說明書	Product Datasheet Protocol
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