TRIM25 Antibody (Center)

APR04146G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR04146G		100 μl / ￥4950

大規(guī)格詢價(jià)

1 Images

訂購(gòu)信息

安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
Inquiry@annoron.com

全國(guó)授權(quán)代理商

TRIM25 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR04146G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRIM25 Antibody (Center).
分子量	70973 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Note=Colocalized with DDX58 at cytoplasmic perinuclear bodies
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	277-306 aa
靶點(diǎn)	This TRIM25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human TRIM25.
亞型	Rabbit Ig
通用名	EFP, RNF147, ZNF147
基因ID	7706
UniProt ID	Q14258
功能	Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs.
總結(jié)	The protein encoded by this gene is a member of thetripartite motif (TRIM) family. The TRIM motif includes threezinc-binding domains, a RING, a B-box type 1 and a B-box type 2,and a coiled-coil region. The protein localizes to the cytoplasm.The presence of potential DNA-binding anddimerization-transactivation domains suggests that this protein mayact as a transcription factor, similar to several other members ofthe TRIM family. Expression of the gene is upregulated in responseto estrogen, and it is thought to mediate estrogen actions inbreast cancer as a primary response gene.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	TRIM25 Antibody (Center) (Cat. APR04146G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TRIM25 antibody detected the TRIM25 protein (arrow).
說明書	Product Datasheet Protocol
數(shù)量

加入購(gòu)物車詢價(jià)

上一產(chǎn)品：ATF2 Antibody (Center T339) 下一產(chǎn)品：CD8A (Cytotoxic- & Suppressor T-Cell Marker) Antibody - With BSA and Azide

熱銷產(chǎn)品

產(chǎn)品添加成功！

購(gòu)物車已有 0 件產(chǎn)品

繼續(xù)訂購(gòu) 查看訂購(gòu)單

加入詢價(jià)單成功！

詢價(jià)單已有 0 件產(chǎn)品

繼續(xù)詢價(jià) 查看詢價(jià)單

選擇	品牌	貨號(hào)	產(chǎn)品名稱	規(guī)格	分類	研究領(lǐng)域	說明書	數(shù)量	目錄價(jià)
1	Leading Biology	APR05963G	EGFR Antibody (Y1092)	100 μl	Polyclonal Antibodies				￥4950.00	訂購(gòu) 詢價(jià)
2	Leading Biology	APR03116G	BRCA1 Antibody (aa1847-1863)	100 μl	Polyclonal Antibodies				￥4950.00	訂購(gòu) 詢價(jià)
3	Leading Biology	AMM05633G	Bombesin Receptor 2 (extracellular) Antibody	50 μl	Polyclonal Antibodies				￥6950.00	訂購(gòu) 詢價(jià)
4	Leading Biology	APR10986G	AP3B1 Antibody (aa2-14)	50 μg	Polyclonal Antibodies				￥4950.00	訂購(gòu) 詢價(jià)
5	Leading Biology	APR11512G	Bestrophin-1 (extracellular) Antibody	50 μl	Polyclonal Antibodies				￥6950.00	訂購(gòu) 詢價(jià)
6	Leading Biology	APG01407G	A3 Adenosine Receptor Antibody	50 μl	Polyclonal Antibodies				￥6950.00	訂購(gòu) 詢價(jià)

最新加入的商品

最新加入的商品

全部產(chǎn)品分類