PDCD4 Antibody (Center)

APR03897G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR03897G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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PDCD4 Antibody (Center)

品牌	Leading Biology	貨號	APR03897G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDCD4 Antibody (Center).
分子量	51735 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm. Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457. Exported from the nucleus in the absence of serum
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	121-149 aa
靶點	This PDCD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human PDCD4.
亞型	Rabbit Ig
通用名	H731
基因ID	27250
UniProt ID	Q53EL6
功能	Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).
總結(jié)	This gene encodes a protein localized to the nucleus inproliferating cells. Expression of this gene is modulated bycytokines in natural killer and T cells. The gene product isthought to play a role in apoptosis but the specific role has notyet been determined. Two transcripts encoding different isoformshave been identified.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:2000 IHC-P~~1:10~50
圖像	All lanes : Anti-PDCD4 Antibody (Center) at 1:2000 dilution Lane 1: 293 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST. All lanes : Anti-PDCD4 Antibody (Center) at 1:2000 dilution Lane 1: 293 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: HL-60 whole cell lysate Lane 5: Jurkat whole cell lysate Lane 6: mouse thymus lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Anti-PDCD4 Antibody (Center) at 1:2000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
說明書	Product Datasheet Protocol
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