品牌 |
Leading Biology |
貨號 |
APR03669G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality POU6F2 Antibody (N-term).
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分子量 |
73265 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
34-61 aa
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靶點(diǎn) |
This POU6F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human POU6F2.
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亞型 |
Rabbit Ig
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通用名 |
RPF1
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基因ID |
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UniProt ID |
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功能 |
Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA.
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總結(jié) |
This gene encodes a member of the POU protein familycharacterized by the presence of a bipartite DNA binding domain,consisting of a POU-specific domain and a homeodomain, separated bya variable polylinker. The DNA binding domain may bind to DNA asmonomers or as homo- and/or heterodimers, in a sequence-specificmanner. The POU family members are transcriptional regulators, manyof which are known to control cell type-specific differentiationpathways. This gene is a tumor suppressor involved in Wilms tumor(WT) predisposition. Alternatively spliced transcript variantsencoding distinct isoforms have been found for this gene.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
POU6F2 Antibody (N-term) (Cat. APR03669G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the POU6F2 antibody detected the POU6F2 protein (arrow).
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說明書 |
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數(shù)量 |
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