品牌 |
Leading Biology | 貨號 |
APR03616G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HMMR Antibody (C-term).
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分子量 |
84100 Da
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細胞定位 |
Antigen Cellular Localization:
Cell surface. Cytoplasm.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
668-697 aa
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靶點 |
This HMMR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-697 amino acids from the C-terminal region of human HMMR.
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亞型 |
Rabbit Ig
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通用名 |
IHABP, RHAMM
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基因ID |
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UniProt ID |
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功能 |
Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity.
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總結(jié) |
The protein encoded by this gene is involved in cellmotility. It is expressed in breast tissue and together with otherproteins, it forms a complex with BRCA1 and BRCA2, thus ispotentially associated with higher risk of breast cancer.Alternatively spliced transcript variants encoding differentisoforms have been noted for this gene.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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圖像 |
All lanes : Anti-HMMR Antibody (C-term) at 1:2000 dilution Lane 1: K562 whole cell lysates Lane 2: LNCaP whole cell lysates Lane 3: HL-60 whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 84 kDa Blocking/Dilution buffer: 5% NFDM/TBST. HMMR Antibody (C-term) (Cat. APR03616G) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the HMMR antibody detected the HMMR protein (arrow). HMMR Antibody (C-term) (Cat. APR03616G)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HMMR Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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