品牌 |
Leading Biology |
貨號(hào) |
APR06183G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality K0776 Antibody (Center).
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分子量 |
89595 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum. Cytoplasm, cytosol
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
426-455 aa
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靶點(diǎn) |
This K0776 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the Central region of human K0776.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysine residues of proteins that may play a crucial role in a number of cellular processes. Mediates DDRGK1 ufmylation and may regulate the proteasomal degradation of DDRGK1 and CDK5RAP3 thereby modulating NF-kappa-B signaling (PubMed:20018847, PubMed:20164180, PubMed:20228063, PubMed:25219498). May also through TRIP4 ufmylation play a role in nuclear receptors-mediated transcription (PubMed:25219498).
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Western blot analysis of K0776 Antibody (Center) (Cat. APR06183G) in MCF-7 cell line lysates (35ug/lane). K0776 (arrow) was detected using the purified Pab.
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說(shuō)明書(shū) |
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數(shù)量 |
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