品牌 |
Leading Biology | 貨號 |
APR06165G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FBXL5 Antibody (N-term).
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分子量 |
78555 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, perinuclear region
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
86-115 aa
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靶點(diǎn) |
This FBXL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-115 amino acids from the N-terminal region of human FBXL5.
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亞型 |
Rabbit Ig
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通用名 |
FBL4, FBL5, FLR1
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基因ID |
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UniProt ID |
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功能 |
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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圖像 |
Western blot analysis of FBXL5 Antibody (N-term) (Cat. APR06165G) in HepG2 cell line lysates (35ug/lane). FBXL5 (arrow) was detected using the purified Pab; Western blot analysis of FBXL5 Antibody (N-term) (Cat. APR06165G) in mouse heart tissue lysates (35ug/lane). FBXL5 (arrow) was detected using the purified Pab. FBXL5 Antibody (N-term) (Cat. APR06165G) IHC analysis in formalin fixed and paraffin embedded testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXL5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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