IL31 Antibody (N-term)

APR06163G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR06163G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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IL31 Antibody (N-term)

品牌	Leading Biology	貨號	APR06163G
產品分類	Polyclonal Antibodies	研究領域
產品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL31 Antibody (N-term).
分子量	18205 Da
細胞定位	Antigen Cellular Localization: Secreted.
宿主	Rabbit
種屬反應性	Human
免疫原	13-40 aa
靶點	This IL31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human IL31.
亞型	Rabbit IgG
基因ID	386653
UniProt ID	Q6EBC2
功能	Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
總結	IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
圖像	Western blot analysis of lysates from K562 cell line and human placenta tissue lysate (from left to right), using IL31 Antibody (N-term)(Cat. APR06163G). APR06163G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. Formalin-fixed and paraffin-embedded human testis tissue reacted with IL31 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. IL31 Antibody (N-term) (Cat. APR06163G) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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