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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > ADIPOR1 Antibody (C-term)

ADIPOR1 Antibody (C-term)

貨號 貨期 規(guī)格 / 價格 詢價
APR06109G 100 μl / ¥4950

ADIPOR1 Antibody (C-term)

品牌

Leading Biology

貨號

APR06109G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADIPOR1 Antibody (C-term).

分子量

42616 Da

細(xì)胞定位

Antigen Cellular Localization: Membrane; Multi-pass membrane protein Note=Localized to the cell membrane and intracellular organelles

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

305-331 aa

靶點(diǎn)

This ADIPOR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-331 amino acids from the C-terminal region of human ADIPOR1.

亞型

Rabbit Ig

通用名

PAQR1, TESBP1A

基因ID

UniProt ID

功能

Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.

總結(jié)

The adiponectin receptors, ADIPOR1 and ADIPOR2, serve as receptors for globular and full-length adiponectin and mediate increased AMPK and PPAR-alpha ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, FC, E

稀釋方法

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

圖像

Anti-ADIPOR1 Antibody (C-term) at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of ADIPOR1 Antibody (C-term) (Cat. APR06109G) in Y79 cell line lysates (35ug/lane). ADIPOR1 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human hepatocarcinoma with ADIPOR1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

說明書

數(shù)量

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