DUSP13-M1 Antibody (N-term)

APR06085G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR06085G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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DUSP13-M1 Antibody (N-term)

品牌	Leading Biology	貨號	APR06085G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DUSP13-M1 Antibody (N-term).
分子量	22149 Da
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	1-30 aa
靶點(diǎn)	This DUSP13-M1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP13-M1.
亞型	Rabbit Ig
通用名	DUSP13B, TMDP
基因ID	51207
UniProt ID	Q9UII6
功能	Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.
總結(jié)	Dual-specificity phosphatases, a subfamily of protein-tyrosine phosphatases, play important roles in signal transduction, cell cycle progression, and tumor suppression. The cDNA encoding a novel phosphatase, PIR1, phosphatase that interacts with RNA/RNP complex 1. Sequence analysis revealed that the predicted 329-amino acid protein has homology to several dual-specificity phosphatases and contains 2 stretches of arginine-rich sequence similar to those found in some RNA-binding proteins. In vitro, recombinant protein displays protein-tyrosine phosphatase activity and binds directly to RNA.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100
圖像	Western blot analysis of DUSP13 (arrow) using DUSP13-M1 Antibody (N-term) (Cat.APR06085G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DUSP13 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
說明書	Product Datasheet Protocol
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