ARTS1 Antibody (Center)

APR06018G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR06018G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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ARTS1 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR06018G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARTS1 Antibody (Center).
分子量	107235 Da
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass type II membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	451-480 aa
靶點(diǎn)	This ARTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the Central region of human ARTS1.
亞型	Rabbit Ig
通用名	APPILS, ARTS1, KIAA0525
基因ID	51752
UniProt ID	Q9NZ08
功能	Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
總結(jié)	Aminopeptidases play a role in the metabolism of several peptides that may be involved in blood pressure and the pathogenesis of essential hypertension. Adipocyte-derived leucine aminopeptidase (ALAP) is a member of the M1 family of zinc metallopeptidases.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	Western blot analysis of anti-ARTS1 Antibody (Center) (Cat.APR06018G) in Ramos cell line lysates (35ug/lane). ARTS1 (arrow) was detected using the purified Pab.
說(shuō)明書	Product Datasheet Protocol
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