PALA Antibody (N-term)

APR05812G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR05812G		100 μl / ￥4950

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PALA Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR05812G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PALA Antibody (N-term).
分子量	129696 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	162-189 aa
靶點(diǎn)	This PALA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-189 amino acids from the N-terminal region of human PALA.
亞型	Rabbit Ig
通用名	KIAA1358
基因ID	25851
UniProt ID	Q7Z6L1
功能	Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P, WB, FC, E
稀釋方法	IHC-P~~1:50~100 WB~~1:1000 FC~~1:10~50
圖像	Formalin-fixed and paraffin-embedded human brain tissue reacted with PALA Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of PALA Antibody (N-term) (Cat. APR05812G) in A375 cell line lysates (35ug/lane). PALA (arrow) was detected using the purified Pab. PALA Antibody (N-term) (Cat. APR05812G) flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說(shuō)明書(shū)	Product Datasheet Protocol
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