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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > SPPL3 Antibody (N-term)

SPPL3 Antibody (N-term)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR05741G 100 μl / ¥4950

SPPL3 Antibody (N-term)

品牌

Leading Biology

貨號(hào)

APR05741G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPPL3 Antibody (N-term).

分子量

42563 Da

細(xì)胞定位

Antigen Cellular Localization: Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Restricted to the early secretory compartment

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

50-81 aa

靶點(diǎn)

This SPPL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-81 amino acids from the N-terminal region of human SPPL3.

亞型

Rabbit Ig

通用名

IMP2, PSL4

基因ID

UniProt ID

功能

Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.

總結(jié)

Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

圖像

Western blot analysis of SPPL3(arrow) using rabbit polyclonal SPPL3 Antibody (N-term) (Cat.APR05741G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SPPL3 gene (Lane 2) (Origene Technologies).

說(shuō)明書

數(shù)量

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