品牌 |
Leading Biology | 貨號(hào) |
APR05602G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYOZ1 Antibody (Center).
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分子量 |
31745 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
40-69 aa
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靶點(diǎn) |
This MYOZ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the Central region of human MYOZ1.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
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總結(jié) |
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. This protein plays an important role in the modulation of calcineurin signaling, may play a role in myofibrillogenesis.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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圖像 |
Western blot analysis of MYOZ1 Antibody (Center) (Cat. APR05602G) in MDA-MB231 cell line lysates (35ug/lane).MYOZ1 (arrow) was detected using the purified Pab. MYOZ1 Antibody (Center) (Cat. APR05602G) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MYOZ1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. MYOZ1 Antibody (Center) (Cat. APR05602G) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說(shuō)明書(shū) |
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數(shù)量 |
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