品牌 |
Leading Biology | 貨號 |
APR05600G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL5RA Antibody (N-term).
|
||
分子量 |
47685 Da
|
||
細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
|
||
宿主 |
Rabbit
|
||
種屬反應(yīng)性 |
Human
|
||
免疫原 |
49-76 aa
|
||
靶點 |
This IL5RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-76 amino acids from the N-terminal region of human IL5RA.
|
||
亞型 |
Rabbit Ig
|
||
通用名 |
IL5R
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
This is the receptor for interleukin-5. The alpha chain binds to IL5.
|
||
總結(jié) |
IL5RA is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4.
|
||
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
應(yīng)用 |
WB, IHC-P, FC, E
|
||
稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
|
||
圖像 |
Western blot analysis of lysate from MDA-MB-453 cell line, using IL5RA Antibody (N-term)(Cat. APR05600G). APR05600G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane. IL5RA Antibody (N-term) (Cat. APR05600G) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IL5RA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. IL5RA Antibody (N-term) (Cat. APR05600G) flow cytometric analysis of U251 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
||
說明書 |
|||
數(shù)量 |
|
選擇 | 品牌 | 貨號 | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價 | |
1 | Leading Biology | APR05963G | EGFR Antibody (Y1092) | 100 μl | Polyclonal Antibodies |
|
¥4950.00 | 訂購 詢價 | ||
2 | Leading Biology | APR03116G | BRCA1 Antibody (aa1847-1863) | 100 μl | Polyclonal Antibodies |
|
¥4950.00 | 訂購 詢價 | ||
3 | Leading Biology | AMM05633G | Bombesin Receptor 2 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 訂購 詢價 | ||
4 | Leading Biology | APR10986G | AP3B1 Antibody (aa2-14) | 50 μg | Polyclonal Antibodies |
|
¥4950.00 | 訂購 詢價 | ||
5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 訂購 詢價 | ||
6 | Leading Biology | APG01407G | A3 Adenosine Receptor Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 訂購 詢價 |
微信掃描二維碼,隨時隨地與小諾親密接觸,精彩活動,勁爆優(yōu)惠,觸手可得!