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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Rabbit Anti-HABP2 27 kDa light chain antibody品牌 |
Leading Biology | 貨號 |
APR05485G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Rabbit Anti-HABP2 27 kDa light chain antibody .
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分子量 |
H=63,60;M=62,58;R=62 KDa
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細胞定位 |
Antigen Cellular Localization:
Secreted. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form
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宿主 |
Rabbit
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通用名 |
HGFAL, PHBP
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基因ID |
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UniProt ID |
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功能 |
Cleaves the alpha-chain at multiple sites and the beta- chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro- urokinase) to the active two chain form. Activates coagulation factor VII.
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總結 |
The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB
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稀釋方法 |
WB~~ 1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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