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當(dāng)前位置：首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > CMKLR1 Antibody

CMKLR1 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR05423G 100 μl / ￥4950

CMKLR1 Antibody

品牌

 Leading Biology

貨號(hào)

 APR05423G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CMKLR1 Antibody.

分子量
42 KDa

細(xì)胞定位
Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein

宿主
Rabbit

種屬反應(yīng)性
Human, Mouse, Rat

免疫原
235-262 aa

通用名
CHEMR23, DEZ

基因ID

UniProt ID

功能
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF- kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

總結(jié)
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF- kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB

稀釋方法
WB~~ 1:1000

圖像

Western blot analysis of lysates from Hela,HUVEC cell line (from left to right),using CMKLR1 Antibody(APR05423G). APR05423G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.

說明書

數(shù)量

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