Phospho-mouse TSC1(S1138) Antibody

APR05342G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR05342G		100 μl / ￥4950

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Phospho-mouse TSC1(S1138) Antibody

品牌	Leading Biology	貨號(hào)	APR05342G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-mouse TSC1(S1138) Antibody.
分子量	128746 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Membrane; Peripheral membrane protein. Note=At steady state found in association with membranes.
宿主	Rabbit
種屬反應(yīng)性	Mouse
靶點(diǎn)	This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1138 of mouse TSC1.
亞型	Rabbit Ig
通用名	Kiaa0243
基因ID	64930
UniProt ID	Q9EP53
功能	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
總結(jié)	In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	DB, E
稀釋方法	DB~~1:500
圖像	Dot blot analysis of Mouse TSC1 Antibody (Phospho S1138) Phospho-specific Pab (Cat. APR05342G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
說(shuō)明書(shū)	Product Datasheet Protocol
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