Phospho-MYC(T58) Antibody

APR05172G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR05172G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Phospho-MYC(T58) Antibody

品牌	Leading Biology	貨號	APR05172G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-MYC(T58) Antibody.
分子量	48804 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus, nucleoplasm. Nucleus, nucleolus
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	This MYC Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T58 of human MYC.
亞型	Rabbit Ig
通用名	BHLHE39
基因ID	4609
UniProt ID	P01106
功能	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
總結(jié)	MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	DB, WB, E
稀釋方法	DB~~1:500 WB~~1:1000
圖像	Dot blot analysis of Phospho-MYC-T58 Pab (Cat.APR05172G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. Western blot analysis of Phospho-MYC-T58 Antibody in human TPA activated Hela cell line lysates. Phospho-MYC (arrow) was detected using the purified PAb. (0: without TPA; 1: 60ug/ml TPA, 15min; 2: 60ug/ml TPA, 30min; 3: 60ug/ml TPA, 45min; 4: 125ug/ml TPA, 15min; 5: 125ug/ml TPA, 30min; 6: 125ug/ml TPA, 45min; 7: 250ug/ml TPA, 15min; 8: 250ug/ml TPA, 30min; 9: 250ug/ml, 45min)
說明書	Product Datasheet Protocol
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