品牌 |
Leading Biology | 貨號(hào) |
APR04978G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LLGL2 Antibody (N-term).
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分子量 |
113448 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
165-199 aa
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靶點(diǎn) |
This LLGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human LLGL2.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.
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總結(jié) |
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Western blot analysis of anti-LLGL2 Pab(Cat. APR04978G) in 293 cell line lysate (35ug/lane). LLGL2(arrow) was detected using the purified Pab. |
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說(shuō)明書(shū) |
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數(shù)量 |
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