品牌 |
Leading Biology | 貨號 |
APR04911G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Dsk2 Antibody (N-term).
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分子量 |
65696 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Where it colocalizes with the proteasome. Associated with fibers in mitotic cells
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
20-50 aa
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靶點 |
This Dsk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human Dsk2.
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亞型 |
Rabbit Ig
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通用名 |
N4BP4, PLIC2
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基因ID |
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UniProt ID |
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功能 |
Increases the half-life of proteins destined to be degraded by the proteasome; may modulate proteasome-mediated protein degradation.
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總結(jié) |
Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
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圖像 |
The anti-Dsk2 Pab (Cat. APR04911G) is used in Western blot to detect Dsk2 in HeLa cell lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Dsk2 Antibody (N-term) (Cat.APR04911G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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