STAG2 Antibody (N-term)

APR04732G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR04732G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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STAG2 Antibody (N-term)

品牌	Leading Biology	貨號	APR04732G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STAG2 Antibody (N-term).
分子量	141326 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of cohesin is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation. In germ cells, cohesin complex dissociates from chromatin at prophase I, and may be replaced by a meiosis-specific cohesin complex
宿主	Rabbit
種屬反應(yīng)性	Human
靶點	This STAG2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 61-94 amino acids from the N-terminal region of human STAG2.
亞型	Rabbit Ig
通用名	SA2
基因ID	10735
UniProt ID	Q8N3U4
功能	Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
總結(jié)	Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	Western blot analysis of lysates from Hela, MCF-7 cell line (from left to right), using STAG2 Antibody (N-term)(APR04732G). APR04732G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
說明書	Product Datasheet Protocol
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