USP21 Antibody (Center)

APR04568G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR04568G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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USP21 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR04568G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality USP21 Antibody (Center).
分子量	62656 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	226-256 aa
靶點(diǎn)	This USP21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-256 amino acids from the Central region of human USP21.
亞型	Rabbit Ig
通用名	USP23
基因ID	27005
UniProt ID	Q9UK80
功能	Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
總結(jié)	USP21 is a ubiquitin-specific protease, an enzyme that removes ubiquitin from ubiquitinated proteins. The encoded protein belongs to the C19 peptidase family, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. This protein has been reported to be capable of removing NEDD8 from NEDD8 conjugates.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	Western blot analysis of hUSP21-L241 (Cat. APR04568G) in NCI-H460 cell line lysates (35ug/lane). USP21 (arrow) was detected using the purified Pab.
說(shuō)明書(shū)	Product Datasheet Protocol
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