品牌 |
Leading Biology | 貨號(hào) |
APR04536G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SPNXB Antibody (Center).
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分子量 |
11826 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Associated with nuclear craters
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
17-47 aa
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靶點(diǎn) |
This SPNXB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the Central region of human SPNXB.
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亞型 |
Rabbit Ig
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通用名 |
SPANXB
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基因ID |
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UniProt ID |
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總結(jié) |
Temporally regulated transcription and translation ofseveral testis-specific genes is required to initiate the series ofmolecular and morphological changes in the male germ cell lineagenecessary for the formation of mature spermatozoa. This gene is amember of the SPANX family of cancer/testis-associated genes, whichare located in a cluster on chromosome X. The SPANX genes encodedifferentially expressed testis-specific proteins that localize tovarious subcellular compartments. This particular gene maps tochromosome X in a head-to-tail orientation with SPANX family memberB1 and appears to be a duplication of that locus. The SPANXB genesare unique members of this gene family, since they contain anadditional 18 nt in their coding region compared to the majority offamily members. Although the protein encoded by this gene containsconsensus nuclear localization signals, the major site forsubcellular localization of expressed protein is in the cytoplasmicdroplets of ejaculated spermatozoa. This protein provides abiochemical marker for studying the unique structures inspermatazoa, while attempting to further define its role inspermatogenesis.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
SPNXB Antibody (Center) (Cat. APR04536G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SPNXB antibody detected the SPNXB protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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