RGS2 Antibody (N-term)

APR04526G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR04526G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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RGS2 Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR04526G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RGS2 Antibody (N-term).
分子量	24382 Da
細(xì)胞定位	Antigen Cellular Localization: Isoform 1: Cell membrane. Cytoplasm. Nucleus, nucleolus Isoform 3: Cell membrane. Cytoplasm. Nucleus, nucleolus
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	4-32 aa
靶點(diǎn)	This RGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human RGS2.
亞型	Rabbit Ig
通用名	G0S8
基因ID	5997
UniProt ID	P41220
功能	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
總結(jié)	Regulator of G protein signaling (RGS) family members areregulatory molecules that act as GTPase activating proteins (GAPs)for G alpha subunits of heterotrimeric G proteins. RGS proteins areable to deactivate G protein subunits of the Gi alpha, Go alpha andGq alpha subtypes. They drive G proteins into their inactiveGDP-bound forms. Regulator of G protein signaling 2 belongs to thisfamily. The protein acts as a mediator of myeloid differentiationand may play a role in leukemogenesis.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	RGS2 Antibody (N-term) (Cat. APR04526G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RGS2 antibody detected the RGS2 protein (arrow).
說(shuō)明書	Product Datasheet Protocol
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