全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR04428G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCNDBP1 Antibody(N-term).
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分子量 |
40262 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus.
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
21-49 aa
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靶點 |
This CCNDBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human CCNDBP1.
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亞型 |
Rabbit Ig
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通用名 |
DIP1, GCIP, HHM
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基因ID |
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UniProt ID |
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功能 |
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription.
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總結 |
This gene was identified by the interaction of its geneproduct with Grap2, a leukocyte-specific adaptor protein importantfor immune cell signaling. The protein encoded by this gene wasshown to interact with cyclin D. Transfection of this gene in cellswas reported to reduce the phosphorylation of Rb gene product bycyclin D-dependent protein kinase, and inhibit E2F1-mediatedtranscription activity. This protein was also found to interactwith helix-loop-helix protein E12 and is thought to be a negativeregulator of liver-specific gene expression. Several alternativelyspliced variants have been found for this gene. [provided byRefSeq].
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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