全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR04386G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RASA3 Antibody (C-term).
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分子量 |
95699 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
594-623 aa
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靶點(diǎn) |
This RASA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-623 amino acids from the C-terminal region of human RASA3.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.
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總結(jié) |
The protein encoded by this gene is member of the GAP1family of GTPase-activating proteins. The gene product stimulatesthe GTPase activity of normal RAS p21 but not its oncogeniccounterpart. Acting as a suppressor of RAS function, the proteinenhances the weak intrinsic GTPase activity of RAS proteinsresulting in the inactive GDP-bound form of RAS, thereby allowingcontrol of cellular proliferation and differentiation. This familymember is an inositol 1,3,4,5-tetrakisphosphate-binding protein,like the closely related RAS p21 protein activator 2. The twofamily members have distinct pleckstrin-homology domains, with thisparticular member having a domain consistent with its localizationto the plasma membrane.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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