品牌 |
Leading Biology |
貨號(hào) |
APR04352G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GMCL1L Antibody (C-term).
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分子量 |
60201 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus matrix.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
498-524 aa
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靶點(diǎn) |
This GMCL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-524 amino acids from the C-terminal region of human GMCL1L.
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亞型 |
Rabbit Ig
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通用名 |
GCL, GMCL1L
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UniProt ID |
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功能 |
Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity). Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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總結(jié) |
GMCL1L is possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity). Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Anti-GMCL1L Antibody (C-term) at 1:1000 dilution + human testis lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 60 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
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說(shuō)明書 |
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數(shù)量 |
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