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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > mouse BAD Antibody (Center S112/S111/Y113)品牌 |
Leading Biology | 貨號(hào) |
APR04343G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality mouse BAD Antibody (Center S112/S111/Y113).
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分子量 |
22080 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse
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免疫原 |
90-118 aa
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靶點(diǎn) |
This mouse BAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of mouse BAD.
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亞型 |
Rabbit Ig
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通用名 |
Bbc6
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基因ID |
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UniProt ID |
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功能 |
Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
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總結(jié) |
BAD promotes cell death. It successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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