mouse BAD Antibody (Center S112/S111/Y113)

APR04343G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR04343G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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mouse BAD Antibody (Center S112/S111/Y113)

品牌	Leading Biology	貨號(hào)	APR04343G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality mouse BAD Antibody (Center S112/S111/Y113).
分子量	22080 Da
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm
宿主	Rabbit
種屬反應(yīng)性	Mouse
免疫原	90-118 aa
靶點(diǎn)	This mouse BAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of mouse BAD.
亞型	Rabbit Ig
通用名	Bbc6
基因ID	12015
UniProt ID	Q61337
功能	Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
總結(jié)	BAD promotes cell death. It successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	All lanes : Anti-mouse BAD Antibody at 1:1000 dilution Lane 1: A20 whole cell lysate Lane 2: C2C12 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 22 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Mouse BAD Antibody (Center S112/S111/Y113) (Cat. APR04343G) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the BAD antibody detected the BAD protein (arrow).
說(shuō)明書	Product Datasheet Protocol
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mouse BAD Antibody (Center S112/S111/Y113)