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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > CD1B Antibody (N-term)

CD1B Antibody (N-term)

貨號 貨期 規(guī)格 / 價格 詢價
APR04319G 100 μl / ¥4950

CD1B Antibody (N-term)

品牌

Leading Biology

貨號

APR04319G

產品分類

Polyclonal Antibodies

研究領域

產品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD1B Antibody (N-term).

分子量

36939 Da

細胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Localizes to cell surface lipid rafts

宿主

Rabbit

種屬反應性

Human

免疫原

57-85 aa

靶點

This CD1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human CD1B.

亞型

Rabbit Ig

基因ID

UniProt ID

功能

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

總結

This gene encodes a member of the CD1 family oftransmembrane glycoproteins, which are structurally related to themajor histocompatibility complex (MHC) proteins and formheterodimers with beta-2-microglobulin. The CD1 proteins mediatethe presentation of primarily lipid and glycolipid antigens of selfor microbial origin to T cells. The human genome contains five CD1family genes organized in a cluster on chromosome 1. The CD1 familymembers are thought to differ in their cellular localization andspecificity for particular lipid ligands. The protein encoded bythis gene localizes to late endosomes and lysosomes via atyrosine-based motif in the cytoplasmic tail, and requiresvesicular acidification to bind lipid antigens. [provided byRefSeq].

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, E

稀釋方法

WB~~1:1000

圖像

Western blot analysis of CD1B (arrow) using rabbit polyclonal CD1B Antibody (N-term) (Cat. APR04319G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1B gene.

說明書

數量

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