全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR04309G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEPSECS Antibody (C-term).
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分子量 |
55726 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
444-474 aa
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靶點 |
This SEPSECS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-474 amino acids from the C-terminal region of human SEPSECS.
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亞型 |
Rabbit Ig
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通用名 |
TRNP48
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基因ID |
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UniProt ID |
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功能 |
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.
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總結(jié) |
The 21st amino acid, selenocysteine (sec), is distinctfrom other amino acids because it lacks its own tRNA synthetase andis the only amino acid synthesized on its cognate tRNA. Synthesisof sec begins with acylation of tRNA(sec) (TRSP; MIM 165060) byseryl-tRNA synthetase (SARS; MIM 607529) to give ser-tRNA(sec),which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase(PSTK; MIM 611310) to give O-phosphoseryl-tRNA(sec). SEPSECScatalyzes the final step of sec synthesis by convertingO-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) usingselenophosphate as the selenium donor (Palioura et al., 2009[PubMed 19608919]).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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