SERPINB11 Antibody (Center)

APR04300G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR04300G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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SERPINB11 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR04300G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SERPINB11 Antibody (Center).
分子量	44099 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	170-196 aa
靶點(diǎn)	This SERPINB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-196 amino acids from the Central region of human SERPINB11.
亞型	Rabbit Ig
基因ID	89778
UniProt ID	Q96P15
功能	Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change.
總結(jié)	SerpinB11 is a serine proteinase inhibitor of the ovalbumin-like B clade of serpins. It was first discovered in human lung and prostate. Little is known about SerpinB11 tissue distribution and function. Splice variants of 305, 278 and 190 amino acids have been reported, with predicted masses of 33.97, 31.6 and 21.1 kDa respectively, and pIs of 8.11, 9.03 and 6.07 respectively. The 305 and 190 amino acid forms share the same aminoterminus as the 392 amino acid form. The 305 amino acid form has a deletion in residues 120-206, of the 392 amino acid form. The 190 amino acid form has a deletion in residues 57-259 relative to the long form. The 278 amino acid form starts at the third methionine, relative to the long form. All four forms contain the reactive center loop of the long form, but it is unknown if the shorter forms are active serpins. The predicted isoelectric points of SerpinB11 are significantly more basic than the other B clade serpins, and suggest a different localization or function for this serpin.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	SERPINB11 Antibody (Center) (Cat. APR04300G) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SERPINB11 antibody detected the SERPINB11 protein (arrow).
說明書	Product Datasheet Protocol
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